Mencoba mengikuti jejak 2 teman kita dengan blog yang edukatif yaitu Bang Jon dan Shila, gw juga mau ikut dong...tp maaf ne sebelumnya kalo gambarnya aq motong sendiri, aq cari2 gak ada... Tp ini bagus banget lho penjelasannya mengenai reaksi hipersensitifitas tipe cepat dan lambat.
Nanti akhirnya granule content, PG dan leukotrien tu menghasilkan IMMEDIATE RESPONSE (vasodilatasi, kebocoran plasma dan spasme otot. Pada alergi IMMEDIATE RESPONSE ini yang langsung keluar saat kita terpapar allergen, tapi LATE-PHASE RESPONSE yang menyebabkan setelah 2-8 jam timbul alergi lagi. Oiya nantinya salah satu granule content yaitu IL-5 dan Leukotrien B bersama-sama merangsang pengeluaran eosinofil lho,itu sebabnya eosinofil meningkat pada keadaan alergi.
Reaksi hipersensitifitas itu sendiri ada 4 macam, yaitu Immediate (type I), Antibody-mediated (type II), Immune complex-mediated (type III)dan T-cell-mediated (type IV).
Banyak pertanyaan mengenai apakah alergi ini merupakan suatu sifat yang dapat diturunkan, namun sampai sekarang masih dilakukan penelitian yang lebih lanjut mengapa reksi hipersensitivitas pada setiap individu tidak sama lebih-lebih belum diketahui pola pemunculan sifat tersebut. Penelitian lain membuktikan bahwa anak kembar identik memiliki persamaan kesensitifan hanya sebesar 90%.
2 komentar:
Nice Putri! Btw, at the exam for lecturers selection last year we had a question about hypersensitivity reaction! A classic work in medicine I think.
Immunogenetics is actually a very interesting field as well (also, talking about parasitology and infectious disease always involves discussion about immune-mediated response and genetic polymorphism).
Allergic disease is now mostly considered as "multifactorial" disease, genetics is only a predisposition factor and difference of degree of expression between individuals may be influenced by environmental/epigenetics factors.
^_^ Sorry for stopping by uninvited.
RNT
thank you mbak ajeng for the comment.
yeah the allergic response still be a mystery because it multifactorial characteristic.
Why it can appear in one person, but in the other not. Even it as a twin.
I don't know I really interested in the differences of identic twin. They're so unique for me, they're twin but somestimes can be so different,,,haha
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